Study Purpose: The purpose of this study is to identify genetic and dietary factors that affect the risk for non-alcoholic fatty liver disease.
Recruiting: Caucasians, ages 18-40 with no history of alcohol abuse
What participants will do: On the first visit participants will provide saliva samples. Selected participants will return to undergo an acute, and a 3-week oral fructose challenge for a total of 5 visits. Each visit, participants will provide blood, urine, and stool samples, as well as fill out a questionnaire.
There are 3 phases for participants:
Phase 1: providing a saliva sample for screening
Phase 2, visit 1: MRI scan in Winston-Salem
Phase 2, visit 2: acute challenge day –provide blood and urine samples and blood pressure measurements at 3 time points. Participants will also collect fructose sugar drinks for a 3-week chronic challenge.
Phase 3, visit 1: MRI scan in Winston-Salem
Phase 3, visit 2: acute challenge day –provide blood and urine samples and blood pressure measurements at 3 time points
Compensation: Eligible participants will be compensated.
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Post: May 4, 2018