Manya Warrier, PhD
- The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance.
- The immunophilin ligands cyclosporin A and FK506 suppress prostate cancer cell growth by androgen receptor-dependent and -independent mechanisms.
- Scavenger receptor class B type I is a plasma membrane cholesterol sensor.
- Intestinal SR-BI does not impact cholesterol absorption or transintestinal cholesterol efflux in mice.
- Intestinal microbiota metabolism of L-carnitine, a nutrient in red meat, promotes atherosclerosis.
- Susceptibility to diet-induced hepatic steatosis and glucocorticoid resistance in FK506-binding protein 52-deficient mice.
Manya Warrier, PhD, joined the UNC Nutrition Research Institute in 2015 as assistant professor. Her research focus is the “browning” of fat and its effects on metabolism and obesity. Dr. Warrier specializes in cell signaling, cell biology, protein expression, biochemistry and metabolic syndromes.
She is a member of the American Heart Association (AHA) and the Endocrine Society.
Dr. Warrier earned her Master of Science in Biotechnology at the University of Mysore (India) and received her PhD in Biomedical Sciences at the University of Toledo. At Toledo she concentrated on cardiovascular and metabolic diseases and went on to a predoctoral fellowship in the field. She performed her postdoctoral studies at Wake Forest University. From 2011-2014 she was a Postdoctoral Research Fellow at the Cleveland Clinic foundation located in the Wake Forest School of Medicine where she investigated the role of trimethylamine N oxide (TMAO) generating enzyme Flavin Monooxygenase 3 (FMO3) in energy metabolism. She has won various awards, including: Early Career Investigator Travel Award, Postdoctoral Scholar Development Award at Wake Forest University, Keystone Symposia Scholarship (2008), and Elsa Albrecht Fellow Award from the Cleveland Clinic for “Outstanding Publication.”