Sergey Krupenko, PhD

Professor, Nutrition
Vitamin folate and its role in liver function and cancer disease

Sergey A. Krupenko, PhD, joined the UNC Nutrition Research Institute in 2014. Dr. Krupenko’s research focuses on vitamin folate and its role in liver function and cancer disease. His goal is to understand how we can fight cancer by controlling the diet and nutrient supplements. “There are molecular strings in the human organism, which can be pulled by right combinations of nutrients to activate resistance to tumor formation or to slow down cancer development. We have to identify these links and make them work,” he said. Dr. Krupenko has received his Bachelor’s Degree in Biochemistry from Byelorussian State University and PhD in Biochemistry at the Byelorussian Academy of Sciences. Before joining the NRI, he was a faculty member in the Department of Biochemistry, Vanderbilt University School of Medicine and in the Department of Biochemistry and Molecular Biology, Medical University of South Carolina. He has a joint appointment as a Professor of Nutrition at the Gillings School of Global Public Health, UNC-Chapel Hill.





Research Team


Claire Gates : <h4>Research Technician, Sergey Krupenko Lab</h4>

Claire Gates

Research Technician, Sergey Krupenko Lab

Claire Gates received Bachelor's degrees in Biology, with a concentration in cellular physiology, and Chemistry from UNCC in 2019. Her previous research focused on the elucidation and characterization of pathways involved in bacterial glycan synthesis. She is currently serving as a research technician in the Sergey Krupenko group, who are interested in the influence of folate on liver function and carcinogenesis. She hopes to begin her PhD in Biochemistry in 2020.

Evan Paules : <h4>Graduate Student, S. Zeisel Lab</h4>

Evan Paules

Graduate Student, S. Zeisel Lab

Evan Paules joined the NRI in August 2016 as a doctoral student in the Nutrition Department. He completed his undergraduate program at Rider University in Lawrenceville, NJ. He received his BS in 2016 with a double major in Biochemistry and Behavioral Neuroscience. His research interests include folate metabolism with relation to its role within the central nervous system, as well as cellular homeostasis. Evan was a 4-year member of Rider University’s Division 1 swim team.

Jaspreet Sharma, PhD : <h4>Postdoctoral Research Associate, S. Krupenko Lab</h4>

Jaspreet Sharma, PhD

Postdoctoral Research Associate, S. Krupenko Lab

Jaspreet Sharma joined the NRI in the summer of 2017 in the S. Krupenko’s Lab to investigate the role of folate-metabolizing enzymes in cancer progression and metastasis. She received her PhD from the Graduate Program in the Department of Gastroenterology, PGIMER, Chandigarh (India). Her graduate studies focused on prevention of colon cancer by dietary supplements. She has received her postdoctoral training in the Department of Radiation Oncology at the University of Colorado, Denver, working on the receptor-mediating signaling in tumorigenesis.